PGD for aneuploidy screening (PGS)

Clinical data

D3 biopsy

D5 biopsy
(blastocyst)

Total

No. of cycles

205

86

291

No. of couples

187

69

256

Age (average)

38.4±4.1

37.5±4.3

38.7±7.5

No. of embryos analysed

1533

296

1829

Mean per cycle

7.5

3.4

6.3

No. of embryos diagnosed (%)

1431 (93.3)

282 (95.3)

1713 (93.6)

No. of aneuploid embryos (%)

1118 (78.1)

183 (64.9)

1301 (72.4)

No. of embryos transferred

226

49

275

Mean embryos transferred

1.8

1.5

1.7

No. of transfers (%)

128 (62.4)

33 (38.4)

161 (50.5)

No. +HCG (%)

85 (66.4)

25 (75.8)

110 (68.3)

No. of biochemical pregnancies

9

3

12

No. of early miscarriages (<12 weeks)

9*

0

9*

No. of ongoing clinical pregnancies (%/ET)

74 (57.8)

22 (66.7)

96 (59.6)

No. of Fetal Sacs

100 (44.2)

25 (51.0)

125 (45.5)

No. of Fetal Hearth Beat (FHB)

95

22

117

Implantation rate (%/ET)

44.2%

51.0%

45,5%

No. of advanced abortions (>12 weeks)

3

0

3

No. of deliveries

71

22

93

No. of babies born

90

22

112

Live birth rate (%/ET)

55.5%

66.7%

57,8%

 * Normal karyotype after array-CGH testing of 4 POC

 

La presente casistica si riferisce ai soli casi di diagnosi preimpianto per screening delle aneuploidie cromosomiche, effettuati mediante la tecnica array-CGH, e non include i casi effettuati mediante le tecnologie precedenti (FISH e PCR).

Dati aggiornati 31 Dicembre 2011